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anastrozole will increase the amount or influence of pazopanib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.Otesezonale, a BCRP inhibitor, may boost the effects and threat of toxicities of BCRP substrates. Use cheapest setting up dose of BCRP substrate, or contemplate cutting down BCRP substrate dose